What is the primary advantage of using a statin in patients with elevated cholesterol?

The primary advantage of using a statin in patients with elevated cholesterol is its ability to reduce the risk of cardiovascular events. Statins work by inhibiting an enzyme involved in cholesterol production in the liver, leading to decreased levels of low-density lipoprotein (LDL) cholesterol. Elevated LDL cholesterol is a significant risk factor for the development of atherosclerosis and cardiovascular diseases, including heart attacks and strokes.

Clinical studies have consistently shown that statins not only lower LDL cholesterol levels but also lead to a substantial reduction in major adverse cardiovascular events in various populations, particularly in individuals who are at elevated risk due to factors such as age, existing heart disease, diabetes, or high cholesterol levels. This protective effect on the cardiovascular system is a central reason why statins are widely prescribed as part of cardiovascular risk management.

While statins might have some effects related to other aspects of health, such as possibly having moderate effects on certain markers of inflammation or event rates in diabetes, their primary role and the most significant benefit remain in lowering cardiovascular risk through cholesterol management. This clear link between statin therapy and reduced cardiovascular event rates underpins the rationale for their use in patients with elevated cholesterol levels.