Which option is a commonly used agent for treating acute prostatitis?

The commonly used agent for treating acute prostatitis is ciprofloxacin. This fluoroquinolone antibiotic is effective against the bacteria that are frequently involved in cases of acute bacterial prostatitis, particularly Escherichia coli and other Enterobacteriaceae. Fluoroquinolones like ciprofloxacin reach adequate concentrations in the prostatic tissue, making them particularly suitable for treating infections in this region.

In contrast, trimethoprim-sulfamethoxazole is not the first-line treatment despite some efficacy, primarily because fluoroquinolones have a better penetration and act against the common pathogens associated with acute prostatitis. Levofloxacin can also be an effective treatment option as it shares similar characteristics with ciprofloxacin, but typically it is used when there are specific known sensitivities or resistance issues. Amoxicillin, while being an antibiotic, is not typically effective against the bacteria that cause acute prostatitis due to its lack of coverage against gram-negative bacilli. Thus, ciprofloxacin is preferred for its efficacy, tissue penetration, and ease of use in clinical practice for this condition.